Recent Advances in Vibrating Mesh Atomizer Enable Innovative Technology in Spray Drying: A Review
DOI:
https://doi.org/10.48048/tis.2026.12551Keywords:
Atomization, Ultrasonic, Piezoelectric, Mesh, Particle, Spray dryingAbstract
Spray drying derived for the synthesis of nano or submicron-sized powders with distinct functionalization and structure. Even after decades of development, producing fine droplets with a uniform size distribution and high production rate in an atomizer is still a challenge. The purpose of this study is to review the significance of the latest advances in ultrasonic atomization and how they have affected spray drying technology, which is essential to the improvement of powder synthesis and processing. Furthermore, ultrasonic atomization can be used to evaluate the usefulness of developed in powder engineering for a variety of applications. These observations offer important insights into the behavior of the droplets generated by the ultrasonic atomizer inside the particular spray dryer reactors that are being used. Numerous researchers have reported their innovations in spray dryer equipped with either Ultrasonic Vibrating Mesh Atomizers (UVM-As) and Surface Acoustic Wave Atomizer (SAW-As) which is known as Ultrasonic Atomizer. Understanding the fundamentals of ultrasonic atomization enables the advancement of spray dryer innovations and technology. Therefore, recent advances in spray drying technology indicate that more compact system designs can be achieved without compromising energy efficiency, thereby contributing to improved overall process performance. In this context, systematic evaluation of atomizer performance is essential at the early stages of atomizer development, particularly in terms of droplet size distribution, energy consumption, and operational stability. Based on the collective findings reported in the literature, vibrating mesh atomizer-assisted spray drying has demonstrated significant potential for producing finer particles with narrower size distributions, making it a promising atomization approach for advanced spray drying applications.
HIGHLIGHTS
- Reviews recent advances and innovations in ultrasonic vibrating mesh atomizers.
- Highlights research progress of ultrasonic atomizer in spray drying
- Evaluates spray drying applications for productions of nano- and micro-particle.
- Identifies challenges and pathways for industrial-scale implementation.
GRAPHICAL ABSTRACT
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D Yonata, YNS Ulvie, E Soesanto, E Sulistyowati, B Pranata and A Rosidi. Stabilization and controlled release of curcumin from temulawak by spray-drying microencapsulation with composite wall materials. Trends in Sciences 2025; 22(2), 9125.
M Munoz-Ibanez, C Azagoh, BN Dubey, E Dumoulin and C Turchiuli. Changes in oil-in-water emulsion size distribution during the atomization step in spray-drying encapsulation. Journal of Food Engineering 2015; 167, 122-132.
KT Kopp, M De Beer, J Voorspoels, D van Lysebetten and G van den Mooter. Spray drying for protein stabilization. International Journal of Pharmaceutics 2025; 677, 125600.
SY Azhary, D Purnama, FF Florena, M Vanitha, Muchtaridi, C Panatarani and IM Joni. Synthesis and characterization of chitosan: SiO2 nanocomposite by ultrasonic spray drying. IOP Conference Series: Materials Science and Engineering 2019; 550(1), 012037.
M Singlard, A Paillassa, L Ferres, C Pagnoux and A Aimable. Freeze granulation and spray drying of mixed granules of Al2O3. Powder Technology 2022; 395, 280-289.
K Samborska, S Poozesh, A Barańska, M Sobulska, A Jedlińska, C Arpagaus, N Malekjani and SM Jafari. Innovations in spray drying process for food and pharma industries. Journal of Food Engineering 2022; 321, 110960.
P Teeragaroonwong, C Hudthagosol, N Laohakunjit, N Onsri and P Sanporkha. Spray drying of inca peanut meal protein hydrolysate to produce protein powder drink mix. Trends in Sciences 2024; 21(11), 8371.
Y Tian, N Fu, WD Wu, D Zhu, J Huang, S Yun and XD Chen. Effects of co-spray drying of surfactants with high solids milk on milk powder wettability. Food and Bioprocess Technology 2014; 7(11), 3121-3135.
C Draheim, F Crécy, S Hansen, EM Collnot and CM Lehr. A design of experiment study of nanoprecipitation and nano spray drying as processes to prepare plga nano-and microparticles with defined sizes and size distributions. Pharmaceutical Research 2015; 32(8), 2609-2624.
N Wijayanti, TD Widyaningsih, SN Wulan and M Rifai. Influence of spray drying inlet temperature on the physical properties and antioxidant activity of black garlic extract powder. Trends in Sciences 2024; 21(2), 7247.
A Velázquez-Palenzuela, H Wang, N Yang, K Dam-Johansen and JM Christensen. Preparation of TiO2-based hollow microspheres by spray drying and their use as novel active pigments for photocatalytic coatings. Progress in Organic Coatings 2021; 160, 106518.
DE Walton and CJ Mumford. The morphology of spray-dried particles: The effect of process variables upon the morphology of spray-dried particles. Chemical Engineering Research and Design 1999; 77(5), 442-460.
DA Miller, D Ellenberger, T Porfirio and M Gil. Spray-drying technology. In: RO Williams, DA Davis and DA Miller (Eds.). Formulating poorly water-soluble drugs. Springer International Publishing, Cham, Switzerland, 2022, p. 377-452.
DL Yang, RK Liu, Y Wei, Q Sun and JX Wang. Micro-sized nanoaggregates: Spray-drying-assisted fabrication and applications. Particuology 2024; 85, 22-48.
K Almansour, R Ali, F Alheibshy, TJ Almutairi, RF Alshammari, N Alhaj, C Arpagaus and MMA Elsayed. Particle engineering by nano spray drying: Optimization of process parameters with hydroethanolic versus aqueous solutions. Pharmaceutics 20222; 14(4), 800.
D Santos, AC Maurício, V Sencadas, JD Santos, MH Fernandes and PS Gomes. Spray drying: An overview. In: R Pignatello and T Musumeci (Eds.). Biomaterials - physics and chemistry. IntechOpen, London, 2018.
ME Sivamma and R Snehitha. Atomization techniques in spray drying: A review. The Pharma Innovation Journal 2021; 10(5), 454-461.
OZ Olszewski, R Macloughlin, A Blake, M O’Neill, A Mathewson and N Jackson. A silicon-based MEMS vibrating mesh nebulizer for inhaled drug delivery. Procedia Engineering 2016; 168, 1521-1524.
IC Kemp, T Hartwig, R Herdman, P Hamilton, A Bisten and S Bermingham. Spray drying with a 2-fluid nozzle to produce fine particles: Atomization, scale-up, and modeling. Drying Technology 2019; 34(10), 1243-1252.
PD Hede, P Bach and AD Jensen. Two-fluid spray atomization and pneumatic nozzles for fluid bed coating/agglomeration purposes: A review. Chemical Engineering Science 2008; 63(14), 3821-3842.
P Höhne, B Mieller and T Rabe. Advancing spray granulation by ultrasound atomization. International Journal of Applied Ceramic Technology 2020; 17(5), 2212-2219.
VT Mantripragada, K Kumar, P Kumar and S Sarkar. Modeling of powder production during centrifugal atomization. Journal of Sustainable Metallurgy 2021; 7(2), 620-629.
Z Yang, J Yu, J Duan, X Xu and G Huang. Optimization-design and atomization-performance study of aerial dual-atomization centrifugal atomizer. Agriculture 2023; 13(2), 1-19.
J Zhang, Q Yan and W Sun. Advances in piezoelectric atomizers. Transactions of Nanjing University of Aeronautics and Astronautics 2020; 37(1), 54-69.
H Li, J Liu, K Li and Y Liu. Piezoelectric micro-jet devices: A review. Sensors and Actuators A: Physical 2019; 297, 111552.
Y Lei and H Hu. SAW-driven droplet jetting technology in microfluidic: A review. Biomicrofluidics 2020; 14(6), 61505.
RW Wood and AL Loomis. The physical and biological effects of high-frequency sound-waves of great intensity. The London, Edinburgh, and Dublin Philosophical Magazine and Journal of Science 1927; 4(22), 417-436.
M Ashokkumar, F Cavalieri, F Chemat and K Okitsu. Handbook of ultrasonics and sonochemistry. Springer, Singapore, 2016.
MK Tan, JR Friend, OK Matar and LY Yeo. Capillary wave motion excited by high frequency surface acoustic waves. Physics of Fluids 2010; 22(11), 112112.
Y Zhang, S Yuan and L Wang. Investigation of capillary wave, cavitation and droplet diameter distribution during ultrasonic atomization. Experimental Thermal and Fluid Science 2020; 120, 110219.
Y Zhang and S Yuan. Phase, pressure and velocity evolution and atomization characteristics of multiple Faraday waves in ultrasonic atomization: Experiments and simulations. International Journal of Multiphase Flow 2022; 156(37), 104223.
NAH Hadi and A Ahmad. Experimental study of the characteristics of acoustic cavitation bubbles under the influence of ultrasonic wave. IOP Conference Series: Materials Science and Engineering 2020; 808(1), 012042.
H Naidu, O Kahraman and H Feng. Novel applications of ultrasonic atomization in the manufacturing of fine chemicals, pharmaceuticals, and medical devices. Ultrason Sonochem 2022; 86, 105984.
R Lang. Ultrasonic atomization of liquids. Acustica 1962; 341(1954), 28-30.
K Yasuda, K Mochida, Y Asakura and S Koda. Separation characteristics of alcohol from aqueous solution by ultrasonic atomization. Ultrasonics Sonochemistry 2014; 21(6), 2026-2031.
R Rajan and AB Pandit. Correlations to predict droplet size in ultrasonic atomization. Ultrasonics 2001; 39(4), 235-255.
K Yasuda, H Honma, Y Asakura and S Koda. Effect of frequency on ultrasonic atomization. Symposium on Ultrasonic Electronics 2010; 31, 363-364.
K Yasuda, K Mochida, Y Asakura and S Koda. Separation characteristics of alcohol from aqueous solution by ultrasonic atomization. Ultrasonics Sonochemistry 2014; 21(6), 2026-2031.
K Yasuda, Y Bando, S Yamaguchi, M Nakamura, A Oda and Y Kawase. Analysis of concentration characteristics in ultrasonic atomization by droplet diameter distribution. Ultrasonics Sonochemistry 2005; 12(1-2), 37-41.
K Yasuda, Y Nohara and Y Asakura. Effect of ultrafine bubbles on ethanol enrichment using ultrasonic atomization. Japanese Journal of Applied Physics 2020; 59, SKKD09.
LX Huang, K Kumar and AS Mujumdar. A comparative study of a spray dryer with rotary disc atomizer and pressure nozzle using computational fluid dynamic simulations. Chemical Engineering and Processing: Process Intensification 2006; 45(6), 461-470.
JJ O’Sullivan, EA Norwood, JA O’Mahony and AL Kelly. Atomisation technologies used in spray drying in the dairy industry: A review. Journal of Food Engineering 2019; 243, 57-69.
MN Patil, AB Pandit and BN Thorat. Ultrasonic atomisation assisted spray drying. In: Proceedings of the 5th Asia-Pacific Drying Conference, Hong Kong, China. 2007, p. 255-261.
IC Jacobs. Atomization and spray-drying processes. In: AG Gaonkar, N Vasisht, AR Khare and R Sobel (Eds.). Microencapsulation in the food industry. Academic Press, New York, 2014, p. 47-56.
ME Sivamma and R Snehitha. Atomization techniques in spray drying: A review. The Pharma Innovation Journal 2021; 10(5), 454-461.
ABD Nandiyanto and K Okuyama. Progress in developing spray-drying methods for the production of controlled morphology particles: From the nanometer to submicrometer size ranges. Advanced Powder Technology 2011; 22(1), 1-19.
K Almansour, R Ali, F Alheibshy, TJ Almutairi, RF Alshammari, N Alhajj, C Arpagaus and MMA Elsayed. Particle engineering by nano spray drying: Optimization of process parameters with hydroethanolic versus aqueous solutions. Pharmaceutics 2022; 14(4), 800.
F Liu, N Kang, Y Li and Q Wu. Experimental investigation on the atomization of a spherical droplet induced by Faraday instability. Experimental Thermal and Fluid Science 2019; 100, 311-318.
Q Yan, W Sun, L Zhang, H Wang and J Zhang. Effects of vibration characteristics on the atomization performance in the medical piezoelectric atomization device induced by intra-hole fluctuation. Chinese Journal of Mechanical Engineering 2021; 34(1), 123.
E Guerra-Bravo, HJ Lee, A Baltazar and KJ Loh. Vibration analysis of a piezoelectric ultrasonic atomizer to control atomization rate. Applied Sciences 2021; 11(18), 8350.
M Panão. Ultrasonic atomization: New spray characterization approaches. Fluids 2022; 7(1), 29.
Z Lu, ED Dupuis, VK Patel, AM Momen and S Shahab. Ultrasonic oscillatory 2-phase flow in microchannels. Physics of Fluids 2021; 33(3), 032003.
JL Liang, F Zhang, JH Zhang, WQ Huang, YX Wen and BC Chen. Improvement of mesh atomizer performance by electrolytic polishing. Applied Sciences 2023; 13(4), 2572.
M Beck-Broichsitter. Polymer-coated aperture plates for tailored atomization processes. Materials Science and Engineering C 2018; 110, 110666.
D Heng, SH Lee, WK Ng and RBH Tan. The nano spray dryer B-90. Expert Opinion on Drug Delivery 2011; 8(7), 965-972.
P Sharma, M Quazi, IR Vazquez and N Jackson. Investigation of droplet size distribution for vibrating mesh atomizers. Journal of Aerosol Science 2022; 166, 106072.
YM Kuo, WH Chan, CW Lin, SH Huang and CC Chen. Characterization of vibrating mesh aerosol generators. Aerosol and Air Quality Research 2019; 19(8), 1678-1687.
SH Moon, KH Chang, HM Park, BJ Park, SK Yoo and KC Nam. Effects of driving frequency and voltage on the performances of vibrating mesh nebulizers. Applied 2021; 11(3), 1296.
Q Yan, W Sun and J Zhang. Study on the influencing factors of the atomization rate in a piezoceramic vibrating mesh atomizer. Applied Sciences 2020; 10(7), 2422.
M Trapuzzano, A Tejada-Martínez, R Guldiken and N Crane. Volume and frequency-independent spreading of droplets driven by ultrasonic surface vibration. Fluids 2020; 5(1), 18.
J Ju, Y Yamagata, H Ohmori and T Higuchi. High-frequency surface acoustic wave atomizer. Sensors and Actuators A: Physical 2008; 145, 437-441.
E Mahravan, H Naderan and E Damangir. Frequency and wavelength prediction of ultrasonic induced liquid surface waves. Ultrasonics 2016; 72, 184-190.
Y Zhang, S Zhang, Y Xu, X Deng, S Zhao, Y Tian and Y Tang. Experimental study and analysis on the atomization performance of a single micro-droplet motivated by high-frequency ultrasound. Applied Thermal Engineering 2025; 279, 127628.
SH Moon, KH Chang, HM Park, BJ Park, SK Yoo and KC Nam. Effects of driving frequency and voltage on the performances of vibrating mesh nebulizers. Applied Sciences 2021; 11(3), 1296.
P Deepu, C Peng and S Moghaddam. Dynamics of ultrasonic atomization of droplets. Experimental Thermal and Fluid Science 2018; 92, 243-247.
Q Yan, C Wu and J Zhang. Effect of the dynamic cone angle on the atomization performance of a piezoceramic vibrating mesh atomizer. Applied Sciences 2019; 9(9), 1836.
Q Yan, J You, W Sun, Y Wang, H Wang and L Zhang. Advances in piezoelectric jet and atomization devices. Applied Sciences 2021; 11(11), 5093.
J Zhang, Q Yan and W Sun. Advances in piezoelectric atomizers. Transactions of Nanjing University of Aeronautics and Astronautics 2020; 37(1), 54-69.
Z Hou, L Wang, X Yan, Z Wang and L An. Study on characteristics of the cavitation bubble dynamics of lithium bromide aqueous solution with ultrasonic interaction. Journal of Building Engineering 2021; 44, 102424.
T Xiong, G Liu, S Huang, G Yan and J Yu. Two-phase flow distribution in parallel flow mini/micro-channel heat exchangers for refrigeration and heat pump systems: A comprehensive review. Applied Thermal Engineering 2022; 201, 117820.
YD Lang and JH Zhang. Influence of piezoelectric atomizer pores on ultrasonic atomization effect. In: Proceedings of the 2014 Symposium on Piezoelectricity, Acoustic Waves and Device Applications, Beijing, China, p. 287-290.
M Beck-Broichsitter, IE Paulus, A Greiner and T Kissel. Modified vibrating-mesh nozzles for advanced spray-drying applications. European Journal of Pharmaceutics and Biopharmaceutics 2015; 92, 96-101.
M Beck-Broichsitter, C Schweiger, T Schmehl, T Gessler, W Seeger and T Kissel. Characterization of novel spray-dried polymeric particles for controlled pulmonary drug delivery. Journal of Controlled Release 2012; 158(2), 329-335.
M Beck-Broichsitter, MC Knuedeler, W Seeger and T Schmehl. Controlling the droplet size of formulations nebulized by vibrating-membrane technology. European Journal of Pharmaceutics and Biopharmaceutics 2014; 87(3), 524-529.
M Muñoz, S Goutier, S Foucaud, G Mariaux and T Poirier. Droplet size prediction in ultrasonic nebulization for non-oxide ceramic powder synthesis. Ultrasonics 2018; 84, 25-33.
T Kudo, K Sekiguchi, K Sankoda, N Namiki and S Nii. Effect of ultrasonic frequency on size distributions of nanosized mist generated by ultrasonic atomization. Ultrasonics Sonochemistry 2017; 37, 16-22.
M Beck-Broichsitter. Aerosol production by vibrating membrane technology: Analysis of the electrolyte effect on generated droplet size and nebulizer output rate. Journal of Pharmaceutical Sciences 2017; 106(8), 2168-2172.
OZ Olszewski, R MacLoughlin, A Blake, M O’Neill, A Mathewson and N Jackson. A silicon-based MEMS vibrating mesh nebulizer for inhaled drug delivery. Procedia Engineering 2016; 168, 1521-1524.
F Zhang, X Huang, B Chen, Y Huo, Z Liu, W Zhang, M Ma, X Zhou, Z Liang, Z Gui and J Zhang. Research on the machinability of micro-tapered hole group in piezoelectric atomizer and the improvement method. Sensors 2022; 22(20), 7891.
J Zhang, Q Yan, J Huang and C Wu. Experimental verification of the pumping effect caused by the micro-tapered hole in a piezoelectric atomizer. Sensors 2018; 18(7), 2311.
Y Cai, J Zhang, C Zhu, J Huang and F Jiang. Theoretical calculations and experimental verification for the pumping effect caused by the dynamic micro-tapered angle. Chinese Journal of Mechanical Engineering 2016; 29(3), 615-623.
M Beck-Broichsitter, IE Paulus, A Greiner and T Kissel. Modified vibrating-mesh nozzles for advanced spray-drying applications. European Journal of Pharmaceutics and Biopharmaceutics 2015; 92, 96-101.
M Kurosawa, T Watanabe, A Futami and T Higuchi. Surface acoustic wave atomizer. Sensors and Actuators A: Physical 1995; 50(1-2), 69-74.
J Friend and LY Yeo. Microscale acoustofluidics: Microfluidics driven via acoustics and ultrasonics. Reviews of Modern Physics 2011; 83(2), 647-704.
A Qi, J Friend and L Yeo. SAW atomization application on inhaled pulmonary drug delivery. Biomedical Applications of Micro-and Nanoengineering IV and Complex Systems 2008; 7270, 198-207.
M Alvarez, J Friend and LY Yeo. Rapid generation of protein aerosols and nanoparticles via surface acoustic wave atomization. Nanotechnology 2008; 19(45), 455103.
S Zhang, J Orosco and J Friend. Onset of visible capillary waves from high-frequency acoustic excitation. Langmuir 2023; 39(10), 3699-3709.
K Suzuki, K Arashi and S Nii. Determination of droplet and vapor ratio of ultrasonically-atomized aqueous ethanol solution. Journal of Chemical Engineering of Japan 2012; 45(5), 337-342.
J Liu and H Feng. Experimental and theoretical analysis of ultrasonic separation in bioethanol purification. Results in Engineering 2024; 24, 102886.
J Liu, AJ Pearlstein and H Feng. Effect of operating parameters on single-stage ultrasonic separation of ethanol from its aqueous solutions. Separation and Purification Technology 2024; 353, 128179.
H Li, JR Friend and LY Yeo. Surface acoustic wave concentration of particle and bioparticle suspensions. Biomed Microdevices 2007; 9(5), 647-656.
P Brunet, M Baudoin, OB Matar and F Zoueshtiagh. Droplet displacements and oscillations induced by ultrasonic surface acoustic waves: A quantitative study. Physical Review E - Statistical, Nonlinear, and Soft Matter Physics 2010; 81(3), 036315.
D Yang, L Haworth, P Agrawal, R Tao, G McHale, H Torun, J Martin, J Luo, X Hou and YQ Fu. Dynamic mitigation mechanisms of rime icing with propagating surface acoustic waves. Langmuir 2022; 38(37), 11314-11323.
JJ Wang, H Hu, A Ye, J Chen and P Zhang. Experimental investigation of surface acoustic wave atomization. Sensors and Actuators A: Physical 2016; 238, 1-7.
KH Choi, HB Kim, K Ali, M Sajid, GU Siddiqui, DE Chang, HC Kim, JB Ko, HW Dang and YH Doh. Hybrid surface acoustic wave- electrohydrodynamic atomization (SAW-EHDA) for the development of functional thin films. Scientific Reports 2015; 5(1), 15178.
Y Ito, K Kushida, K Sugawara and H Takeuchi. A 100-MHz ultrasonic transducer array using ZnO thin films. IEEE IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control 1995; 42(2), 316-324.
Y Ito, K Kushida, K Sugawara and H Takeuchi. Thermodynamic analysis of brine management methods: Zero-discharge desalination and salinity-gradient power production. Desalination 2017; 404, 291-303.
J Ju, Y Yamagata, K Inoue and T Higuchi. A study on atomization characteristics of surface acoustic wave atomizer using laser doppler anemometry. In: K Shirase and S Aoyagi (Eds.). Service robotics and mechatronics. Springer, London, 2010.
A Lozano, H Amaveda, F Barreras, X Jordà and M Lozano. High-frequency ultrasonic atomization with pulsed excitation. Journal of Fluids Engineering, Transactions of the ASME 2003; 125(6), 941-945.
EE Guerra-Bravo, HJ Lee, A Baltazar and KJ Loh. Vibration analysis of a piezoelectric ultrasonic atomizer to control atomization rate. Applied Sciences 2021; 11(18), 8350.
J Villegas Santiago, F Gómez Navarro, A Domínguez Niño, MA García Alvarad, MA Salgado-Cervantes and G Luna-Solano. Effect of spray-drying conditions on moisture content and particle size of coffee extract in a prototype dryer. Revista Mexicana de Ingeniera Quimica 2020; 19(2), 767-781.
M Selvamuthukumaran, C Tranchant and J Shi. Spraying drying: Concept, application and its recent advances in food processing. In: M Selvamuthukumaran (Ed.). Handbook on spray drying applications for food industries. 1st ed. CRC Press, Boca Raton, United States, 2019.
A Sosnik and KP Seremeta. Advantages and challenges of the spray-drying technology for the production of pure drug particles and drug-loaded polymeric carriers. Advances in Colloid and Interface Science 2015; 223, 40-54.
IC Kemp, T Hartwig, R Herdman, P Hamilton, A Bisten and S Bermingham. Spray drying with a 2-fluid nozzle to produce fine particles: Atomization, scale-up, and modeling. Drying Technology 2016; 34(10), 1243-1252.
M Peanparkdee, S Iwamoto and R Yamauchi. Microencapsulation: A review of applications in the food and pharmaceutical industries. Reviews in Agricultural Science 2016; 4, 56-65.
PR Gogate and RA Khaire. Use of ultrasonic atomization for encapsulation and other processes in food and pharmaceutical manufacturing. In: JA Gallego-Juárez, KF Graff and M Lucas (Eds.). Power ultrasonics: Applications of high-intensity ultrasound. 2nd ed. Woodhead Publishing, Sawston, United Kingdom, 2023.
RA Khaire and PR Gogate. Novel approaches based on ultrasound for spray drying of food and bioactive compounds. Drying Technology 2021; 39(12), 1832-1853.
A Dalmoro, AA Barba, G Lamberti and M D’Amore. Intensifying the microencapsulation process: Ultrasonic atomization as an innovative approach. European Journal of Pharmaceutics and Biopharmaceutics 2012; 80(3), 471-477.
JCG Rocha, FAR de Barros, ÍT Perrone, KWC Viana, GM Tavares, R Stephani and PC Stringheta. Microencapsulation by atomization of the mixture of phenolic extracts. Powder Technology 2019; 343, 317-325.
X Li, N Anton, C Arpagaus, F Belleteix and TF Vandamme. Nanoparticles by spray drying using innovative new technology: The büchi nano spray dryer B-90. Journal of Controlled Release 2010; 147(2), 304-310.
AG Büchi Labortechnik. Spray drying & encapsulation solutions - particle formation for lab scale. Buchi Labortechnik, Flawil, Switzerland, 2015.
CI Piñón-Balderrama, C Leyva-Porras, Y Terán-Figueroa, V Espinosa-Solís, C Álvarez-Salas and MZ Saavedra-Leos. Encapsulation of active ingredients in food industry by spray-drying and nano spray-drying technologies. Processes 2020; 8(8), 889.
B Gu, B Linehan and YC Tseng. Optimization of the Büchi B-90 spray drying process using central composite design for preparation of solid dispersions. International Journal of Pharmaceutics 2015; 491(1-2), 208-217.
EM Littringer, S Zellnitz, K Hammernik, V Adamer, H Friedl and NA Urbanetz. Spray drying of aqueous salbutamol sulfate solutions using the nano spray dryer B-90 - The impact of process parameters on particle size. Drying Technology 2013; 31(12), 1346-1353.
A Kyriakoudi and MZ Tsimidou. Properties of encapsulated saffron extracts in maltodextrin using the Büchi B-90 nano spray-dryer. Food Chemistry 2018; 266, 458-465.
SM Jafari, C Arpagaus, MA Cerqueira and K Samborska. Nano spray drying of food ingredients; materials, processing and applications. Trends in Food Science & Technology 2021; 109, 632-646.
R Vehring, WR Foss and D Lechuga-Ballesteros. Particle formation in spray drying. Journal of Aerosol Science 2007; 38(7), 728-746.
R Vehring. Pharmaceutical particle engineering via spray drying. Pharmaceutical Research 2008; 25(5), 999-1022.
M Mezhericher, A Levy and I Borde. Heat and mass transfer of single droplet/wet particle drying. Chemical Engineering Science 2008; 63(1), 12-23.
NNM Eijkelboom, AP van Boven, I Siemons, PFC Wilms, RM Boom, R Kohlus and MAI Schutyser. Particle structure development during spray drying from a single droplet to pilot-scale perspective. Journal of Food Engineering 2023; 337, 111222.
S Chopde, R Datir, G Deshmukh, A Dhotre and M Patil. Nanoparticle formation by nanospray drying & its application in nanoencapsulation of food bioactive ingredients. Journal of Agriculture and Food Research 2020; 2, 100085.
C Anandharamakrishnan and SP Ishwarya. Spray drying techniques for food ingredient encapsulation. IFT Press, Illinois, United States.
G Aladwani, MAM Momin, B Spence, DR Farkas, S Bonasera, A Hassan, M Hindle and W Longest. Effects of different mesh nebulizer sources on the dispersion of powder formulations produced with a new small-particle spray dryer. International Journal of Pharmaceutics 2023; 642, 123138.
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