Endometritis in Cattle: A Review of Current Understanding and Practical Causes of Repeat Breeding

Authors

  • Herry Agoes Hermadi Division of Veterinary Reproduction, Faculty of Veterinary Medicine, Universitas Airlangga, Kampus C Mulyorejo, East Java 60115, Indonesia
  • Aswin Rafif Khairullah Research Center for Veterinary Science, National Research and Innovation Agency (BRIN), West Java 16911, Indonesia
  • Yenny Damayanti Division of Veterinary Anatomy, Faculty of Veterinary Medicine, Universitas Airlangga, Kampus C Mulyorejo, East Java 60115, Indonesia
  • Erma Safitri Division of Veterinary Reproduction, Faculty of Veterinary Medicine, Universitas Airlangga, Kampus C Mulyorejo, East Java 60115, Indonesia
  • Wiwiek Tyasningsih Division of Veterinary Microbiology, Faculty of Veterinary Medicine, Universitas Airlangga, Kampus C Mulyorejo, East Java 60115, Indonesia
  • Sunaryo Hadi Warsito Division of Animal Husbandry, Faculty of Veterinary Medicine, Universitas Airlangga, Kampus C Mulyorejo, East Java 60115, Indonesia
  • Muhammad Khaliim Jati Kusala Research Center for Veterinary Science, National Research and Innovation Agency (BRIN), West Java 16911, Indonesia
  • Syahputra Wibowo Eijkman Research Center for Molecular Biology, National Research and Innovation Agency (BRIN), West Java 16911, Indonesia
  • Ikechukwu Benjamin Moses Department of Applied Microbiology, Faculty of Science, Ebonyi State University, Abakaliki 480211, Nigeria
  • Moh. Adiba Kurniawan Profession Program of Veterinary Medicine, Faculty of Veterinary Medicine, Universitas Airlangga, Kampus C Mulyorejo, East Java 60115, Indonesia
  • Bantari Wisynu Kusuma Wardhani Research Center for Pharmaceutical Ingredients and Traditional Medicine, National Research and Innovation Agency (BRIN), Jl. Raya Bogor Km. 46 Cibinong, Bogor, West Java, 16911, Indonesia
  • Saputro Teguh Prasetyo Profession Program of Veterinary Medicine, Faculty of Veterinary Medicine, Universitas Airlangga, Kampus C Mulyorejo, Jl. Dr. Ir. H. Soekarno, Surabaya, East Java, 60115, Indonesia
  • Dea Anita Ariani Kurniasih Research Center for Public Health and Nutrition, National Research and Innovation Agency (BRIN), West Java 16911, Indonesia
  • Anggreani Desi Ramadhani Rahajeng Profession Program of Veterinary Medicine, Faculty of Veterinary Medicine, Universitas Airlangga, Kampus C Mulyorejo, East Java 60115, Indonesia
  • Ima Fauziah Research Center for Veterinary Science, National Research and Innovation Agency (BRIN), West Java 16911, Indonesia
  • Catherine Britta Vidhianty Profession Program of Veterinary Medicine, Faculty of Veterinary Medicine, Universitas Airlangga, Kampus C Mulyorejo, East Java 60115, Indonesia
  • Arif Nur Muhammad Ansori Medical Biotechnology Research Group, Virtual Research Center for Bioinformatics and Biotechnology, East Java 60493, Indonesia
  • Wasito Wasito Research Center for Veterinary Science, National Research and Innovation Agency (BRIN), West Java 16911, Indonesia
  • Riza Zainuddin Ahmad Research Center for Veterinary Science, National Research and Innovation Agency (BRIN), West Java 16911, Indonesia

DOI:

https://doi.org/10.48048/tis.2025.9587

Keywords:

Cattle, Endometritis, Sexually transmitted disease, T. pyogenes, Uterus

Abstract

One of the most prevalent reproductive illnesses that significantly reduce the livestock industry's profitability is endometritis. Endometritis is an inflammation that occurs in the uterine mucosa (endometrium), which is the inner layer of the uterine wall. Trueperella pyogenes is the most common organism linked to endometritis in cattle. Endometritis is a reproductive condition characterized by signs of repeated breeding. It is evident that there is a correlation between the season of delivery and the occurrence of endometritis, with a higher frequency of endometritis occurring during autumnal deliveries. Although endometritis primarily affects cattle, it can also affect sheep, goats, pigs, horses, and camels. The primary clinical signs of endometritis include an enlarged uterus and an expanded cervical diameter, as well as purulent vaginal discharge. Endometritis is frequently diagnosed using the traditional method based on clinical signs and rectal examination. Cattle can contract endometritis from a variety of sources, including retained fetal membranes, assisted birthing procedures, contamination from dead calves, microbes entering the uterus during delivery, and immunological dysfunction in the genital tract of cows that have recently suffered from dystocia. The standard treatment for endometritis consists of a mix of hormones, such as uterotonics, Nonsteroidal Anti-inflammatory Drugs (NSAIDs), and antibiotics. Important strategies to lower endometritis include the following management practices: Prevention of postpartum metabolic disorders, early detection and treatment of postpartum uterine diseases, and close monitoring and support during delivery.

HIGHLIGHTS

  • This article provides a comprehensive review of endometritis disease in cattle.
  • Endometritis in cattle is an inflammation of the inner lining of the uterus (endometrium), often due to bacterial infection after calving.
  • Endometritis can cause decreased reproductive efficiency and economic losses for the farm.


GRAPHICAL ABSTRACT

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2025-04-20

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