In-vitro Antibacterial and Antifungal Activity of Curcuma Amada Roxb. against Human Pathogens
DOI:
https://doi.org/10.48048/tis.2022.4839Keywords:
Curcuma amada, Rhizome, In-vitro, Antibacterial, AntifungalAbstract
This investigation was conducted to evaluate the antimicrobial effectiveness of the agar disc diffusion method and to determine the inhibition zone of Curcuma amada (CA) rhizome extracts (petroleum ether, dichloromethane, and chloroform) against 12 bacterial species and 4 fungal species. The inhibition zones of the extracts were compared to those of Ciprofloxacin and Griseofulvin for antibacterial and antifungal activities, respectively. The findings revealed that the organisms under examination showed significant inhibition of bacterial as well as fungal development during the experiment and that the typical form of C. amada rhizome can be used to treat bacterial and fungal illnesses. So, this plant could be used to find natural compounds that are bioactive and could be used to make new medicines.
HIGHLIGHTS
- Extracts of amada rhizome were found to protect humans from pathogens
- aureus bacteria had the highest inhibition zone (17 mm) in dichloromethane extract, whereas B. subtilis and B. pumilus bacteria had the lowest inhibition zone (7.5 mm) in C. amada rhizome petroleum ether extract
- notatum in petrolieum ether extract and A. niger in chloroform extract had the highest inhibition zones (13.5 mm), whereas P. funiculosum in chloroform extract of C. amada rhizome had the lowest inhibition zone (10 mm)
GRAPHICAL ABSTRACT
Downloads
Metrics
References
AK Al-Ghamdi, TA Elkholy, S Abuhelal, H Al-Abbadi, D Qahwaji, N Khalefah, H Sobhy and M Abu-Hilal. Phytochemical investigation and In-vitro anthelmintic activity of the leaves of Gynura lycopersicifolia Linn. Pharmacogn. J. 2019; 11, 191-4.
LY. Zhang, JW Wei, ZW Yang, F Chen, QQ Xian, P Su, WY Pan, K Zhang, X Zheng and ZY Du. Distribution and diversity of twelve Curcuma species in China. Nat. Prod. Res. 2017; 32, 327-30.
Y Chen, MK Shukurova, Y Asikin, M Kusano and KN Watanabe. Characterization of volatile organic compounds in mango ginger (Curcuma amada Roxb.) from Myanmar. Metabolites 2021, 11, 1-10.
S Jena, A Ray, A Sahoo, PC Panda and S Nayak. Deeper insight into the volatile profile of essential oil of two Curcuma species and their antioxidant and antimicrobial activities. Ind. Crops Prod. 2020; 155, 1-11.
R Mahadevi and R Kavitha. Phytochemical and pharmacological properties of Curcuma amada: A Review. Int. J. Res. Pharm. Sci. 2020; 11, 3546-55.
S Acharya, DK Patra, C Pradhan and PK Mohapatra. Anti-bacterial, anti-fungal and anti-oxidative properties of different extracts of Bruguiera gymnorrhiza L. (Mangrove). Eur. J. Integr. Med. 2020; 36, 1-7.
G Sharma, S Dang, S Gupta and R Gabrani. Antibacterial Activity, cytotoxicity, and the mechanism of action of bacteriocin from Bacillus subtilis GAS101. Med. Princ. Pract. 2018; 27, 186-92.
NK Kashyap, M Hait, GS Raymahapatra and MM Vaishnav. Proximate and elemental analysis of Careya Arborea Roxb plant’s root. ES food Agrofor. Syst. 2022; 7, 41-7.
M Hait and J Deepak. Physicochemical and phytochemical exploration on non-aerial part of Curcuma amada. J. Pharmacogno. Phytochem. 2018; 7; 1306-9.
L Ying, S Ning, S Hooi-Leng, L Wei, L Yanan, C Cuicui, Z Boxin, H Xuanhe, L Zhihua and JL Yu. Antibacterial activity evaluation and mode of action study of novel thiazole-quinolinium derivatives. RSC Adv. 2020; 10, 15000-14.
S Naz, S Jabeen, S Ilyas, F Manzoor, F Aslam and A Ali. Antibacterial activity of Curcuma longa varieties against different strains of bacteria. Pak. J. Bot. 2010; 42, 455-62.
MI Rahu, SH Ahmed, NN Hussain, M Muhammad, IF Kandhro, N Lodhi, MN Pathan, I Sarker and MA Bhutto. Determination of antimicrobial and phytochemical compounds of Jatropha curcas plant, Saudi J. Biol. Sci. 2021; 28, 2867-76.
RL McMurray, ME Ball, MM Tunney, N Corcionivoschi and C Situ. Anti-bacterial activity of four plant extracts extracted from traditional Chinese medicinal plants against listeria monocytogenes, Escherichia coli, and Salmonella enterica subsp, enterica serovar Enteritidis. Microorganisms 2020; 8, 1-12.
S Henciya, TS Vengateshwaran, MS Gokul, H Dahms and RA James. Antibacterial activity of Halophilic Bacteria against drug‑resistant microbes associated with diabetic foot infections. Curr. Microbiol. 2020; 77, 3711-23.
GS El-Baroty, HA El-Baky, RS Farag and MA Saleh. Characterization of antioxidant and antimicrobial compounds of cinnamon and ginger essential oils. Afr. J. Biochem. Res. 2010; 4, 167-74.
RC Flores, M Ponzi, C Ardanaz, CE Tonn and OJ Donadel. Chemical composition of essential oil of Baccharis salicifolia (Ruiz and Pavon) pers. and antibacterial activity. J. Chil. Chem. Soc. 2009; 54, 475-6.
MT Shaaban, MF Ghaly and SM Fahmi. Antibacterial activities of hexadecanoic acid methyl ester and green-synthesized silver nanoparticles against multidrug-resistant bacteria. J. Basic Microbiol. 2021; 61, 557-68.
CD De Lacerda, JBD Souza, EV Bueno, S Medeiros, ID Cavalcanti and MF Cavalcanti. Antibacterial and anti-biofilm potential of silver nanoparticles against antibiotic-sensitive and multidrug-resistant Pseudomonas aeruginosa strains. Braz. J. Microbiol. 2021; 52, 267-78.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2022 Walailak University
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
